Overview ...
This page is meant to provide an access to on-line materials, software, Web servers and other Web pages that we develop as part of our research, teaching and outreach activities. Our group is part of the Division of Biomedical Informatics at the Children's Hospital Research Foundation (CHRF). CHRF together with the College of Medicine and other departments of the University of Cincinnati form a vibrant center of biomedical research. To learn more about the research environment in Cincinnati follow the links above.
Our research is focused on computational methods in molecular biology and genomics. In short, what we are doing may be classified either as computational biology or bioinformatics, with significant component of pattern recognition and machine learning. We are pursuing research on fundamental problems, such as protein folding process and protein-protein interactions. On a more practical side, we are also interested in developing bioinformatics tools, e.g. for protein structure and function recognition or gene annotation. We are also developing methods for identification of predictive fingerprints of disease states that aim at finding correlation between multiple genomic and clinical attributes with disease states, progression and treatment response. In collaboration with biologists, biochemists and physicians, we are applying standard and our own methods to particular problems at hands.
To read more about our research, collaborative efforts and highlights of projects we are involved in, click here: >>>.
To see home pages of the group members, read about positions or see some photos click here: >>>.
To access Web servers and other tools that we develop (such as LOOPP, SIFT, POLYVIEW, SABLE) click here: >>>.
To access lectures on-line (including my Introduction to Bioinformatics), presentations and other materials click here: >>>.
In
order to access all other pages, please follow the links below and in the
contents frame to the left. There is a number of things that you may find
interesting while shopping around, such as
amino acid page,
molecular dynamics
tutorial, kinases and phosphorylation motifs page,
RPA page,
linear programming and
machine learning benchmarks, fold recognition tutorial etc. Time permitting we will add even more educationally oriented materials
on bioinformatics and computational biology, proteins and protein structure,
molecular dynamics and folding simulations, gene and protein expression profile
analysis etc. Enjoy!
Here is the address and phone number if you prefer to contact us in a traditional way:
Jaroslaw Meller
Children's Hospital Research Foundation, TCHRF-C 8509
3333 Burnet Avenue, Cincinnati, OH 45229
phone: 513-636-0270; fax: 513-636-2056
Jarek Meller, Last update: 1/1/2005.